Psilocybin law in Oregon

Oregon voters passed Measure 109, the Oregon Psilocybin Services Act, in November 2020. The Oregon Health Authority started taking license applications in January 2023, and Oregon became the first state where adults could take psilocybin legally without a diagnosis.¹

How the program works

Adults 21 and older go through three steps with a licensed facilitator: a preparation session, an administration session at a licensed service center where they take psilocybin under supervision, and an optional integration session afterward. No prescription or diagnosis is required.^1,2 Psilocybin products come from licensed manufacturers and must be tested by an accredited laboratory for potency and to confirm the mushroom species.¹⁴

In 2025, the program served 5,935 clients. The health authority's year-end summary listed 25 service center, 11 manufacturer and 377 facilitator licenses for the year.³

A program under strain

The numbers have been hard on businesses. About 20 service centers were actively listed by mid-2026, when InnerTrek, one of the earliest and largest operators in the program, said it would stop holding sessions.⁴ OPB reported that about a third of service centers have closed since licensing began in 2023.⁵

In July 2026, the health authority proposed doubling annual license fees, to $20,000 for service centers and manufacturers and $4,000 for facilitators, and ending discounts for nonprofits, veterans and low-income licensees.⁵ After pushback, it dropped the increase on September 22, 2026, while warning of a budget shortfall. It's now looking at the 15% tax on psilocybin products instead.⁶ Our news story has the details.

The first large outcome study of the program, published in August 2026, followed 346 clients at 24 service centers. Depression, anxiety and PTSD symptoms were lower three months later, and 1.2% of clients had a reaction that needed medical attention. The study had no comparison group.¹³

Local bans

Measure 109 let cities and counties vote to ban psilocybin businesses, and many did. The health authority's tracker records 144 local ordinances and ballot measures that passed, 114 of them permanent bans (some places appear more than once).¹⁰ More votes are coming: Redmond is asking voters on November 3, 2026 whether to extend its moratorium by two years, and Joseph and Reedsport have bans on the same ballot.^15,17,18 See our ballot guide.

Portland's 2026 ordinance

On September 30, 2026, the Portland City Council voted 10 to 0 for the Psychedelic Health and Safety Act, Ordinance 192232. It makes non-commercial personal use, growing and sharing of naturally occurring psychedelics, except peyote, a low enforcement priority for city police.¹¹ It takes effect October 30, 2026, keeps enforcement against sales and impaired driving, and can't override state or federal law.¹²

Recent laws

• HB 4002 (2024) rolled back Measure 110, the 2020 measure that had decriminalized drug possession. Possessing small amounts of psilocybin outside the program became a misdemeanor again.⁷
• HB 2387 (2025) protects licensed health professionals who provide psilocybin services, requires labels to show psilocin potency, and has service centers report clients' veteran status.¹
• HB 4040 (2026), signed April 7, 2026, lets facilitators trained in other states' approved programs, such as Colorado's, apply for Oregon licenses from January 1, 2027.^8,9

What remains illegal

Outside the licensed program, possessing psilocybin in Oregon is a misdemeanor, and growing or selling it is a crime.^1,7 Clients can't take psilocybin home from a service center, and selling it outside the licensed system is illegal under state and federal law. Psilocybin remains a Schedule I drug federally.¹⁶

What to watch

• How the health authority closes its budget gap, including any change to the 15% product tax.
• The November 3 local votes in Redmond, Joseph and Reedsport.
• Out-of-state facilitator licensing under HB 4040, starting January 2027.